Prof. Dr. med. Christine Klein is head of the Institute of Neurogenetics and of the Movement Disorders Section at the Dept. of Neurology at the University of Lübeck.
Together with Prof. Dr. Jens Volkmann she coordinates the Dystonia Translational Research and Therapy Consortium.
She is principle investigator of the project SP2: "German Dystonia Registry: Natural History, Epidemiology, Genetics, and Clinical Trial Resource"
and co-investigator of the project SP4: "Modeling dystonia in an endogenous human cellular system: Platform and characterization of iPSC-derived neurons from patients with monogenic isolated dystonia".
Christine Klein has a large scientific record (>300 peer-reviewed papers) in the field clinical and molecular genetics of dystonia and other movement disorders. The Neurogenetics Institute at the University of Lübeck is a leading research center on the genetics of dystonia.
She is head of the Neurogenetics Committee of the German Neurological Society, has served as Councilor to the Neurogenetics Section of the American Academy of Neurology, is a current member of the Scientific Advisory Board of the Bachmann Strauss Dystonia and Parkinson’s Disease Foundation, and has been a member of the Dystonia Coalition (DC) from its planning phase on.
The Institute of Neurogenetics has state-of-the-art know-how with neuroepidemiology, clinical, and genetic techniques. The Institute’s biobank comprises ~10,000 samples of patients with dystonia and other movement disorders and controls including ~200 fibroblast cultures and several iPS lines of patients with monogenic forms of dystonia.
Christine Klein and her team have identified two new genes for dystonia/dyskinesia in the last years.