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Dystonia Translational Research and Therapy Consortium
- explore phenotypic variability and frequency of mutations in known dystonia genes
- define endophenotypes using neuroimaging or electrophysiology
Dystonia Translational Research and Therapy Consortium
- identify novel disease genes
- elucidate disease mechanisms and identify possible biomarkers and drug targets
Dystonia Translational Research and Therapy Consortium
- identify common final pathophysiological pathways of dystonic motor symptoms
- compare the efficacy of botulinum toxin injection and deep brain stimulation in controlling dystonia-related disability
Dystonia Translational Research and Therapy Consortium
- understand environmental factors
- understand mechanisms of compensation in nonmanifesting mutation carriers
Dystonia Translational Research and Therapy Consortium
DYSTRACT is funded by the German Federal Ministry
of Education and Research.
(2015-2018)